WASHINGTON—Centrist Sen. Thom Tillis (R., N.C.) said he won’t seek re-election in 2026, less than 24 hours after he voted against a motion to advance President Trump’s tax and spending megabill, drawing public backlash from the president.

Republican Sen. Thom Tillis of North Carolina announced Sunday he is not seeking reelection next year, a day after he was one of only two Republicans who voted against advancing President Donald Trump’s sweeping agenda bill.

A Republican US senator from North Carolina has said he will not run for reelection next year, a day after he opposed a sprawling budget bill that is key to President Donald Trump's agenda.Thom Tillis,