A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint ...

There are currently ~38 million people worldwide living with HIV. If left untreated, HIV infection progresses to acquired immunodeficiency syndrome (AIDS) where patients become extremely vulnerable to ...

Monoclonal B-cell lymphocytosis (MBL) is a condition in which a person has an excessive amount of abnormal B cells, which are a type of white blood cell known as lymphocytes. The number of abnormal B ...

Our body's immune system is quick to spring into action when it spots a foreign object that shouldn't be there. Sometimes the ...

However, details of the intervening steps, as researchers have learned in the past 65 years, are quite complex — certain cells carry the flu antigen to the immune system, specific immune cells respond ...

Monoclonal B-cell lymphocytosis is when your body produces an elevated number of identical B cells. In some cases, it can develop into chronic lymphocytic leukemia. Monoclonal B-cell lymphocytosis ...

Casitas B-lineage lymphoma-b (CBLB) is an E3 ubiquitin–protein ligase that functions as an intracellular checkpoint and master negative regulator of T‑cell and natural killer (NK) cell activation, ...