According to new research published in Gastroenterology, the expression and cellular localization of the ion channel cystic fibrosis transmembrane conductance regulator (CFTR) is disrupted by ethanol, ...

New research explains how corticosteroids reduce inflammation and improve secretion of bicarbonate and digestive enzymes in patients with autoimmune pancreatitis—the steroids correct mislocalization ...

Cystic fibrosis could be considered two diseases, one that affects multiple organs including the lungs, and one that doesn't affect the lungs at all, according to a multicenter team. The research ...

The link between acute pancreatitis and chronic pancreatitis is not complete. Indeed, most cases of acute pancreatitis are associated with gallstones, and most cases of recurrent acute pancreatitis ...

What is the recommended approach to the management of acute recurrent idiopathic pancreatitis? The patient has had biliary sphincterotomy and cholecystectomy without benefit. Endoscopic ultrasound ...

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The first CF rat model, CFTR tm1sage (termed CFTR-/- or KO), was designed in collaboration with SAGE (now Horizon Discovery) and subsequently characterized at UAB and distributed to the CF community.

The CFTR Protein Distribution Core offers high-quality, full-length recombinant cystic fibrosis transmembrane conductance regulator (CFTR) proteins expressed in and purified from mammalian cells. Wild ...

Thick mucus that can drown the lungs of a child has long been the hallmark of cystic fibrosis. The hereditary disease affects 30,000 Americans, and patients die unless they receive treatment to clear ...

Please provide your email address to receive an email when new articles are posted on . Patients given aerosolized 4D-710 had elevated CFTR protein levels that went over normal levels. Over 12 months, ...