Elexacaftor/tezacaftor/ivacaftor is an approved treatment for children and adults with cystic fibrosis. Development of docking stations on the respiratory tract is ...
Identifying a mechanistic link between the loss of CFTR function and altered cell-signaling control in CF airway epithelial cells – We have identified a number of cell regulatory changes in CF that ...
Mitogen-Activated Protein Kinase (MAPK) signalling cascades are fundamental to the regulation of numerous cellular processes, including stress response, inflammation, cell cycle control and apoptosis.