The rat basophilic leukemia cell line (RBL) is an excellent model for the investigation of IgE-mediated signal transduction. Recently, we demonstrated that aggregation of the high affinity IgE ...

UNC researchers discovered how a key step in cell signaling works by showing exactly how G proteins detach from receptors ...

Scientists announce in the current issue of the journal Nature their discovery that plants respond to environmental stresses with a sequence of molecular signals known in humans and other mammals as ...

G-protein-coupled receptors (GPCRs) remain major drug targets, despite an incomplete understanding of how they signal through 16 non-visual G-protein signal transducers (collectively named the ...

The muscle regulatory protein myogenin accumulates in differentiating muscle cells when the culture medium is depleted for serum. To investigate the regulation of myogenin gene expression, we have ...