UNC researchers discovered how a key step in cell signaling works by showing exactly how G proteins detach from receptors ...

For more than 70 years, hydralazine has helped doctors lower dangerously high blood pressure during medical emergencies, ...

G-protein-coupled receptors (GPCRs) remain major drug targets, despite an incomplete understanding of how they signal through 16 non-visual G-protein signal transducers (collectively named the ...

An international research group has clarified the action mechanism of incretin-based drugs in the treatment of diabetes. The research group headed by Professor SEINO Susumu included Researcher Okechi ...

Pain, especially chronic pain, is a common neurological phenomenon. The most common chronic pain conditions include low back pain, arthritis pain, migraine and cancer pain—all of which seriously ...

An international research group has clarified the action mechanism of incretin-based drugs (*1) in the treatment of diabetes. The research group headed by Professor SEINO Susumu included Researcher ...

Chemerin is a key adipokine that regulates lipid metabolism and insulin sensitivity, and thus is involved in many metabolic ...