Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse ...
G protein-coupled receptors (GPCRs) have evolved to recognize incredibly diverse extracellular ligands while sharing a common architecture and structurally conserved intracellular signaling partners.
SAN DIEGO--(BUSINESS WIRE)-- Receptos, Inc., a drug discovery and development company, announced today the establishment of a collaboration with Eli Lilly and Company (NYSE:LLY) to research and ...
Deal with Ortho-McNeil-Janssen Pharmaceuticals, Inc. represents blueprint for technology sharing as a new paradigm emerges from Receptos for discovering best-in-class therapeutic drug candidates for ...
A review, by Professors Quast and Margeat from the French National Centre for Scientific Research exploring, has addressed G protein-coupled receptor (GPCR) structural dynamics and the role of ...
SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Septerna, a biotechnology company discovering and advancing novel, oral small molecule medicines targeting G protein-coupled receptors (GPCRs), today ...
Cone photoreceptors mediate daylight vision in vertebrates. Changes in neurotransmitter release at cone synapses encode visual information and is subject to precise control by negative feedback from ...
Scientists from The Scripps Research Institute have determined the structure of a new neurological receptor, A2A adenosine receptor, from within a larger group of four GPCRs that play an essential ...
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