On average, men's levels of prostate-specific antigen (PSA) decrease as their body mass index (BMI) rises, a new study shows.

In this study, researchers evaluated the association between NSAID use, PSA levels, and prostate volume, and hypothesized that men using NSAIDs would have lower PSA levels and prostate volume.

The average PSA levels were 21.6 percent lower among men with a self-reported diagnosis of diabetes compared with men without diabetes.

Hemodilution from increased circulating plasma volumes could explain why obese men with prostate cancer have lower serum PSA levels than non-obese men with the malignancy, according to researchers.