Psoriasis is characterized by hyperproliferation of keratinocytes and increased expression of integrins, but the pathological signaling pathway remains unknown. In August 15 Journal of Clinical ...

Mitogen-activated protein kinase (MAPK) and Wnt signaling pathways are critical for melanocyte development and melanogenesis and could be novel therapeutic targets for modulating melanin synthesis.

Avutometinib plus defactinib granted priority review by FDA, under the accelerated approval pathway, for recurrent KRAS mutant LGSOC; PDUFA action date set for June 30, 2025 Potential U.S. commercial ...

Scientists from Tulane University and The University of Texas at Dallas have discovered a new way that nerve cells communicate – by releasing an enzyme outside the cell that switches on pain signaling ...