A more recent 2020 meta-analysis of 21 trials testing metformin found the drug had a clinically significant impact on ...

A 2020 meta-analysis of 21 metformin trials found the drug had a clinically significant impact on lowering BMI — particularly in folks considered to have obesity. A smaller study on metformin ...

Objective—To summarize the efficacy of metformin in reducing BMI and cardiometabolic risk in obese children and adolescents without diabetes. Research design and methods—We performed a ...

Daily metformin with or without a Mediterranean ... according to findings published in Obesity. Read more. Most adults with overweight or obesity discontinue GLP-1 therapy within 2 years More ...

At baseline, participants without undertaking any antidiabetic agents had HbA1c between 6.5% and 10%, and those taking metformin exhibited HbA1c less than 10%. Individuals with serious ...

We included double-blind RCTs of ≥6 months duration with obese subjects age ≤19 years without diabetes and without secondary or syndromic causes of obesity. Primary outcomes of interest were ...