Future Microbiol. 2012;7(10):1191-1205. HBV and HCV are the two major etiological agents of hepatocellular carcinomas. Aberrant activation of the Notch signaling pathway is found in cells derived from ...
The notch signaling pathway plays a major role in regulating various cellular processes during development, therefore dysregulation of this pathway can lead to disease. This basic signaling pathway ...
Hemodynamic forces and Notch signaling are both known as key regulators of arterial remodeling and homeostasis. However, how these two factors integrate in vascular morphogenesis and homeostasis is ...
A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...
Cancer remains a leading cause of death globally, with lung cancer being particularly lethal. Despite advancements in diagnostics and therapies, the five-year survival rates for advanced tumors have ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 14 (Apr. 3, 2007), pp. 5913-5918 (6 pages) Previous studies have shown that Delta-mediated Notch ...
KS can be classified into four different types [134]. Classic KS is usually an indolent skin disorder primarily affecting Mediterranean elderly men, without relation to HIV infection. Endemic KS is a ...
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