A team of researchers from Academia Sinica and National Taiwan University has identified the Drosophila Cul2 substrate ...

In a major step forward for cancer care, researchers at ChristianaCare's Gene Editing Institute have shown that disabling the ...

(SALT LAKE CITY)—Good news for lifelong exercisers: Along with its salutary effects on the heart, weight, and other facets of health, physical activity also helps to regenerate muscle mass, which ...

Korea Institute of Science and Technology has described nuclear factor erythroid 2-related factor 2 (NFE2L2; NRF2) activators acting as nitric oxide (NO) production inhibitors and antioxidants ...

Image Caption: Mechanisms of resistance to chemoradiotherapy in osteosarcoma. In chemoradiotherapy resistant OS cells, altered expression of the drug transporter proteins, RFC and ABC family, reduces ...

The experimental therapy M102 slowed disease progression in preclinical experiments done in mouse and cell models of ALS, a ...

In non-small-cell lung cancer (NSCLC) and various other cancers, mutations in nuclear factor erythroid 2-related factor 2 ...

Background: Inorganic sodium arsenite (iAs) is a ubiquitous environmental contaminant and is associated with an increased risk of skin hyperkeratosis and cancer. Objectives: We investigated the ...

NF-E2 related factor 2 (Nrf2) was originally defined as a basic leucine zipper (b-Zip) transcriptional activator that recognizes the nuclear factor erythroid 2 (NF-E2)-binding site (Moi et al., 1994; ...

CorriXR Therapeutics, an oncology-focused biotherapeutics company pioneering a ground-breaking gene editing platform technology, InhaTarget Therapeutics, a company dedicated to the early development ...