Identification of the mechanisms of innate immune sensors is fundamental to the understanding of health and disease. The pattern recognition receptor (PRR) subfamily of nucleotide-binding ...
Figure 1: PAMP-PRR interaction in the innate immune response to HIV-1 infection. Remarkably, when monocyte-derived dendritic cells from HIV-1–infected people were exposed to capsid-mutant HIV-1 ...
BOSTON -- Inflammation is at the root of most serious complications occurring after both infection and injury. But while the molecular course of events that leads from microbial infections to the ...
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