Retinoic acid (RA), the most potent biologically active metabolite of vitamin A, induces cell differentiation and growth arrest in a variety of cell types through modifications of expression of ...
Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway
One major unanswered question in apoptosis, an essential process in animal development and homeostasis, is how the cell-suicide program is executed in a highly coordinated fashion so that the dying ...
This is a preview. Log in through your library . Abstract Generation and turnover of phosphoinositides (PIs) must be coordinated in a spatial- and temporal-restricted manner. The small GTPase Rab5 ...
Effect of stents on radiation dosimetry for esophageal cancer. Background: The phosphatidylinositol 3-kinase (PI3K)/Akt (protein kinase B, PKB) signaling pathway plays a critical role in cell growth ...
The phosphoinositide 3-kinase (PI3K)/Akt pathway controls a vast array of normal physiological processes and is frequently aberrantly activated in cancer, thus identifying PI3K/Akt-signaling ...
Palbociclib in Patients With Head and Neck Cancer and Other Tumors With CDKN2A Alterations: Results From the Targeted Agent and Profiling Utilization Registry Study A total of 3.4% (41/1,206) of ...
This review illustrates how the nuclear phosphoinositide-p53 signalosome integrates lipid signaling and p53 function to regulate cancer cell motility. The figure contrasts the tumor-suppressive ...
(RTTNews) - Pharming Group N.V. (PHAR) announced data, including new evidence, from an interim analysis of its open-label extension study evaluating the investigational drug leniolisib, an oral, ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback