Pore-forming toxins (PFTs) produced by sea anemones, most notably the actinoporins, represent a fascinating class of proteins that disrupt target cell membranes through the formation of transmembrane ...

Pore-forming toxins are common bacterial poisons. They attack organisms by introducing holes in cell membranes. A team of scientists at the Technical University of Munich (TUM) has now unraveled the ...

Future Microbiol. 2013;8(1):73-84. Work in the Mulvey laboratory is supported by NIH grants AI095647, AI090369 and AI088086. TJ Wiles was funded by NIH Genetics Training Grant T32-GM007464. The ...

Pore-forming toxins (PFTs) are a diverse class of proteins capable of disrupting cell membranes through the formation of transmembrane channels. These molecular machines play a central role in both ...

Pore-forming toxins are common bacterial poisons. They attack organisms by introducing holes in cell membranes. A team of scientists has now unraveled the mechanism of action for one of these toxins.

Biologists at the EPFL (Ecole Polytechnique Federale de Lausanne) have unveiled a new twist in a metabolic pathway that cells use to defend themselves against toxins made by disease-causing bacteria.

Some types of bacteria have the ability to punch holes into other cells and kill them. They do this by releasing pore-forming toxins (PFTs) that latch onto the cell’s membrane and form a pore.

Pore-forming toxins are common bacterial poisons. They attack organisms by introducing holes in cell membranes. A team of scientists at the Technical University of Munich (TUM) has now unraveled the ...

Using a mouse model that engineered nanosponges can be used to protect eyes from infections caused by Enterococcus faecalis, researchers demonstrate. Enterococcus faecalis contain a toxin called ...

Some types of bacteria kill other cells by releasing proteins called “pore-forming toxins” (PFTs) that create holes in the cell membrane. The PFTs bind to the cell membrane and burrow into, creating a ...

Bacteria are becoming more resistant to the best weapon we have against them: antibiotics. But what if we could live together in peace? Instead of killing the germs, there may be a way to render them ...

Engineers at the University of California, San Diego have invented a “nanosponge” that can safely remove dangerous toxins from the bloodstream – such as those produced by E. coli, poisonous snakes and ...