At the critical intersection between signaling pathways and the process of gene expression, transcription regulation controls and influences many cellular and physiological processes, from cell ...

All three RNAPs have catalytic cores consisting of 10 subunits. Five of these are core subunits which form crab claw shapes with DNA at their centres, channels for RNA products and NTP substrates as ...

The regulation of mRNA transcription plays a key role in relaying signals from the environment and during development into the gene expression program of a cell. During transcription initiation, a ...

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

Also, as the prokaryotic cell lacks a clearly defined nucleus and both transcription and translation takes place in the cytoplasm, there is no need to transport the mRNA to the cytoplasm after ...

Transmembrane signaling involves sensing and communicating with the extracellular environment. Part of the transmembrane signaling is a process known as autoproteolysis, which is key in different ...

Roger Kornberg of the United States won the Nobel Chemistry Prize on Wednesday for work on a key process of life called genetic transcription, building on Nobel prizewinning discoveries by his own ...