Xiaoyan Liu, Weidi Xiao, Yanan Zhang, Sandra E. Wiley, Tao Zuo, Yingying Zheng, Natalie Chen, Lu Chen, Xiaorong Wang, Yawen Zheng, Lan Huang, Shixian Lin, Anne N ...
Researchers from IOCB Prague are furthering the understanding of how medicines work and what it takes to develop their most effective variants. In one current study, they have focused on the disease ...
Booster Therapeutics is developing a novel therapeutic approach that aims to combat the accumulation of deviant proteins in cells, which are a major driver of Parkinson's and other complex diseases ...
Many therapeutic targets escape druggability by mysterious molecular motions that cannot be precisely visualized. This ‘dark-world’ reality is particularly augmented in the ubiquitin-proteasome system ...
The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts. That's still the case, for the most part, but ...
At the recent Celebration of Native Mass Spectrometry in Oxford, we caught up with Michal Sharon to talk about her research and the fascinating evolutionary history of the 20S proteasome. Would you ...
Reporting unexpected processes, chemists say they have discovered how an enzyme known as UCH37 regulates a cell's waste management system. In a new paper with results that senior author Eric Strieter ...
Like any big city, Dr. Nic Lehrbach’s hometown of Sydney, Australia, was in a constant state of change. Old buildings would come down and almost just as quickly new ones would go up. Important to any ...
Booster Therapeutics Awarded Grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to Advance New Class of Proteasome Activator Medicines Towards First-in-Human Phase 1 Study ...
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