Drawing inspiration from natural cell signaling cascades, chemists at Université de Montréal (UdeM) have developed a DNA-based signaling cascade that allows them to quantify and report via an easily ...

Chemists at Université de Montréal have developed "signaling cascades" made with DNA molecules to report and quantify the concentration of various molecules in a drop of blood, all within 5 minutes.

WEST LAFAYETTE, Ind. — Pools of stem cells in the apical meristems of plants are key to continued growth and development. Understanding how these stem cells are maintained and balanced against ...

Smart multi-target drugs are redefining how we treat complex diseases by combining AI-driven discovery with mechanistic ...

All biological processes result from integrated and concerted molecular events. For example, enzyme catalysis is not defined solely by kinetic activity; it is the culmination of a series of events, ...

The canonical Wnt signaling pathway. The left panel (A) demonstrates the activated Wnt signaling cascade, while the right side portrays the inhibited Wnt signaling cascade. Wnt binds to the Fz ...

The sensing principle of these sensors is straightforward: the molecular target or drug to be monitored (shown in green in the illustration above) can interact with a specific DNA molecule, called ...

Nerve damage is one of the most common and burdensome complications of diabetes. Millions of patients worldwide suffer from ...