The gene p53 acts as a tumor suppressor and often is called the ‘guardian of the genome.’ This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading ...

Researchers at the University of Michigan Rogel Cancer Center and School of Dentistry found that certain drugs can change the fundamental makeup of cancer stem cells in mouse models of mucoepidermoid ...

The gene p53 acts as a tumor suppressor and is often called the guardian of the genome. This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading to ...

Scientists have recently shed some light on exactly why elephants, one of the biggest animals on the planet, paradoxically experience unusually low rates of cancer. The research found these remarkable ...

Researchers have elucidated the role of the p53 gene in ulcerative colitis. The study suggests a potential new drug target to stop disease progression to cancer. Researchers in the lab of Michael ...

Please provide your email address to receive an email when new articles are posted on . Matthew S. Davids, MD, MMSc, of Dana-Farber Cancer Institute, explored clinical data on targeting p53-mutant ...

New research led by the University of Bristol has found the protein p53 plays a key role in epithelial migration and tissue repair. The findings could improve our understanding of the processes used ...

An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the ''guardian of the genome'' for its ability to repair DNA damage or destroy cancerous cells. An ...

The tumor suppressing protein p53 has earned the nickname “guardian of the genome” because of its well-studied arsenal of techniques for responding to genetic damage. When it binds to damaged DNA, it ...