Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

Scientists at the Massachusetts Institute of Technology (MIT) have invented a new single-cell nascent RNA sequencing technique that lets them observe the timing of gene and enhancer activation in ...

A research team introduces a new large-scale study on human transcription factors combining two state-of-the art interactomics methods that allow rapid identification of protein-protein interactions ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...

A team of biologists has determined how transcription factors, which guide gene regulation, function differently in embryonic development. The results help illuminate how cells acquire distinct ...

Cells receive a wide variety of cellular and environmental signals, which are often processed combinatorially to generate specific genetic responses. Here we explore theoretically the potentials and ...

Scientists at Penn State University will reveal in the 29 March 2007 issue of the journal Nature the first complete high-resolution map of important structures that control how genes are packaged and ...

Inflammation is a fundamental aspect of the immune system that helps control the spread of pathogens through a variety of cell signaling methods. Yet, in its attempt to “do good,” there are several ...

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s “tail” called phosphorylation patterns. Scientists at St. Jude Children’s ...

Quality control (QC) is vital to the in vitro transcription (IVT) RNA workflow. Because IVT RNA synthesis generates RNA that scientists use in multiple downstream applications, it is critical to start ...