After more than 30 years of intense study, the major intercellular signalling systems that orchestrate embryonic development and tissue maintenance are reasonably well understood. Although there are ...

Please provide your email address to receive an email when new articles are posted on . SCOTTSDALE, Ariz. — The Wnt signaling pathway, neutrophil extracellular traps and PRIME cells represent ...

More than 40 years ago, the wingless gene was discovered in a mutagenesis screen for visual phenotypes, affecting various developmental patterning processes in Drosophila melanogaster. 1 Subsequently, ...

Scientists have made a pivotal breakthrough in understanding the way in which cells communicate with each other. Scientists have made a pivotal breakthrough in understanding the way in which cells ...

Targeting the WNT signaling pathway represents a promising strategy for cancer therapy. The field has evolved to include numerous inhibitors currently under preclinical and clinical investigation.

There is widespread interest in defining factors and mechanisms that stimulate proliferation of pancreatic islet cells. Wnt signaling is an important regulator of organ growth and cell fates, and ...

ANN ARBOR, Mich. – Prostate cancer is a cruel disease. Left untreated, prostate cancer cells often metastasize, or spread, to bone where they form fracture-prone tumors that are extremely painful.

A Wnt/β-catenin pathway agonist under development by Surrozen appears to be effective against idiopathic pulmonary fibrosis (IPF) in mouse models, according to new data. The results, published April 2 ...

A study of 4,699 tumor samples finds Wnt pathway genes CTNNB1 and FAM123B specifically upregulated in colorectal cancer of patients under age 50. While increased screening continues to drive down ...