Researchers have shown that the oncogene-encoded molecule Src is responsible for epithelial cells developing invasive potential and overcoming the normal cellular defense of apical extrusion, but only ...

This is a preview. Log in through your library . The Journal of Cell Biology (JCB) is a not-for-profit publication, edited by scientists, and a leading life sciences journal. The JCB publishes papers ...

Schematic representation of the MucilAir™ pseudostrati ed respiratory epithelium grown on the surface of a porous membrane with culture medium on the basal side and air on the apical side. The goblet ...

In different epithelial cell types, integral membrane proteins appear to follow different sorting pathways to the apical surface. In hepatocytes, several apical proteins were shown to be transported ...

To overcome the challenges of the existing model systems, researchers developed organoids, which are 3D multicellular structures. Organoids contain multiple organ-specific cell types interacting with ...

A recent PLOS Pathogens study analyzed the role played by host mucins and mucin glycans with regard to SARS-CoV-2 entry into the airway epithelial cells. Study: Glycosylated extracellular mucin ...