The San Francisco 49ers may get their top wide receiver back for a Week 11 showdown with the Arizona Cardinals.

Head coach Kyle Shanahan on Monday confirmed the club had a tryout with free agent cornerback Asante Samuel Jr., the son of four-time Pro Bowler and First-Team All-Pro CB Asante Samuel.

What's the Arizona Cardinals vs Seattle Seahawks score? Follow our live score updates for latest news, highlights, analysis ...

Dan Campbell told Fox at halftime "we wanted to mix things up" on offense. He said he was calling plays in Detroit Lions game ...

Sunday was largely unkind to San Francisco. But, the 49ers had several standout performers in its loss versus the Los Angeles Rams.

The Detroit Lions beat the Washington Commanders 44-22 on Sunday, Nov. 9, in Week 10 of the NFL season. Here are the ...

The San Francisco 49ers entered their second matchup against the Los Angeles Rams as underdogs and lost. Here were the worst ...

San Francisco 49ers head coach Kyle Shanahan doesn't have a return date for Brock Purdy, but he gave insight on what the team needs to see from him.

How close was Brock Purdy to playing vs. the Rams? Kyle Shanahan updated his injury status after the 49ers fell against LA.

The San Francisco 49ers have already lost Fred Warner for the year, and now they may have to play without his replacement.

The San Francisco 49ers host the Los Angeles Rams in a huge NFC West matchups. Here's the start time and where to watch.

The San Francisco 49ers defense got some good news when their Week 10 inactives came out. Brock Purdy will not suit up.