The NFL has been around for 100 years, and thousands of great defensive players have come through during that time. From ...

The San Francisco 49ers announced they have signed QB Adrian Martinez to the practice squad and released RB Sincere McCormick from the practice squad. Martinez (6-2, 220) originally entered the NFL ...

The 49ers' exhaustion was written all over their body language Sunday in L.A. Thearon W. Henderson / Getty Images SANTA CLARA, Calif. — Three minutes into Sunday’s game, the San Francisco 49ers ...

It's been more than 400 days since wide receiver Brandon Aiyuk last played a down for the San Francisco 49ers. A second-team All-Pro in the team's run to Super Bowl 58, Aiyuk suffered a major knee ...

The San Francisco 49ers finished their Week 13 contest with a 26-8 win over the Cleveland Browns at Huntington Bank Field. The San Francisco 49ers finished their Week 12 contest with a 20-9 win over ...

The San Francisco 49ers come in as the stronger team, with a balanced offense that leans on their rushing and efficient short-to-intermediate passing game. Mac Jones has been leading the charge, but ...

Niners fans have dominated the crowd at SoFi Stadium in Los Angeles for years, but it’s far from the only stadium they’ve taken over. Ric Tapia / Icon Sportswire via Getty Images SANTA CLARA, Calif. — ...

The wait seems to be over. After six weeks of patiently waiting for Brock Purdy to recover from a second turf toe injury, it seems the 49ers plan to start him this upcoming Sunday against the Arizona ...

The San Francisco 49ers currently sit at the seven seed in the NFC Playoff picture, but there appear to be eight teams fighting for seven spots overall. A win for the 6-5 Carolina Panthers against San ...

The end of the road might be coming for the San Francisco 49ers and wide receiver Brandon Aiyuk. After five seasons, the 49ers are reportedly growing increasingly frustrated with Aiyuk over the past ...