A clinical trial of Vaderis Therapeutics' AKT inhibitor engasertib suggests it could be the first effective treatment for ...

Researchers at the Cornell University College of Veterinary Medicine (CVM) are a step closer to finding the fountain of youth ...

A placebo-controlled trial has shown that the oral AKT inhibitor engasertib could reduce the frequency and duration of ...

Plexiform neurofibromas (PNF) are benign, often infiltrative tumours of the peripheral nerve sheath classically linked to ...

A new mouse study shows high-dose aluminum adjuvant Imject Alum can induce liver fibrosis via inflammasome activation, ...

An aggressive breast cancer lacking common drug targets, triple-negative breast cancer may be countered by oridonin, a ...

Ipatasertib showed significant activity in patients with AKT1E17K mutations, with a 24.1% objective response rate and a median response duration of 10.1 months. The trial's 6-month progression-free ...

A team of researchers from the Germans Trias i Pujol Research Institute (IGTP) and Institut Català d'Oncologia (ICO) has ...

Is moringa oil good for skin? Discover how this nutrient-rich oil hydrates, boosts collagen and supports smoother, healthier ...

A TOR-targeting cancer drug unexpectedly extends yeast lifespan through a newly discovered metabolic feedback loop.

Insilico's generative AI platform, Chemistry42, successfully designed a first-in-class PROTAC targeting PKMYT1 by creating an entirely new inhibitor and its complex linker, demonstrating a powerful, ...

The authors identify the Bearded-type small protein E(spl)m4 as a physical and genetic interactor of TRAF4 in the Drosophila wing disc. These valuable findings with potential biomedical relevance are, ...