Patients with antiphospholipid antibodies (aPL) are at increased risk for arterial or venous thrombosis. There is, however, significant heterogeneity among patients according to clinical and ...

Atrial fibrillation (AF) is a major cause of ischemic stroke, especially in the elderly. There are currently enough data to support the notion that anticoagulation with warfarin or dabigatran is ...

There is controversy regarding the appropriate strategy (anticoagulation vs aspirin) for stroke prevention in low-risk patients (CHA2DS2-VASc score of 0–1). Novel anticoagulants include ...

Inclusion criteria: Adults (18 years old or older) taking antiplatelet drugs for at least 2 weeks; scheduled for elective or emergency neurosurgery under general anaesthesia (craniotomy, spinal cord ...

Overuse of non-aspirin NSAIDs and acetaminophen increases kidney cancer risk by 25-66%, with long-term use damaging kidneys, ...

In an article for The Times, Dr Porter notes: "Nice estimates that 1-2 per cent of the population have medication-overuse headache (MOH) - frequent headaches caused by painkillers and migraine ...

While aspirin has long been the gold standard drug for these patients, researchers say the new data should encourage physicians to try P2Y12 inhibitors to lower the rate of lifetime adverse events.

Resistance and nonresponse to aspirin dramatically decreases its therapeutic efficacy. To overcome this issue, a small-molecule thrombus-targeting drug delivery system, aspirin-Arg-Gly-Asp-Val (A-RGDV ...

High-dose aspirin (HDA) is used with intravenous immunoglobulin (IVIg) in Kawasaki disease (KD). Practice regarding HDA varies, and it is unclear whether HDA duration affects the long-term course.

Additionally, older adults receiving IV ibuprofen were administered on average 33.30mg of morphine vs 43.38mg for those receiving placebo, resulting in a 23.2% reduction in total postoperative ...

Methods Patients were randomised (2 : 1 ratio) to receive naproxen (NPX) 1000 mg daily plus either IFX 5 mg/kg or placebo (PBO) at weeks 0, 2, 6, 12, 18 and 24. The primary efficacy measure was the ...

The NHS is recommending the use of aspirin to help prevent heart attacks and strokes for those vulnerable to them. For anyone that is considered high-risk of either, aspirin contributes to the ...