Metformin, long trusted for diabetes, turns out to work in the brain too. By shutting down Rap1 in the hypothalamus, the drug lowers blood sugar more effectively than previously understood, opening ...

Metformin, the world’s most widely used diabetes drug, has long been recognized for its surprising range of benefits beyond lowering blood sugar, from reducing inflammation to lowering cancer risk.

Although metformin has been the go-to medication to manage type 2 diabetes for more than 60 years, researchers still do not have a complete picture of how it works. Scientists at Baylor College of ...

When Is the Best Time of Day to Take Metformin? We get it — no one enjoys taking medications. It’s just another thing to tackle on your neverending to-do list. If you’ve been prescribed metformin, it ...

Introduction Patients with type 2 diabetes are at risk of microvascular and macrovascular complications. Intensive glycaemic control, especially in patients with short duration of diabetes, is the ...

Objective: LCZ696 is a first-in-class angiotensin receptor neprilysin inhibitor (ARNI) being developed for the treatment of cardiovascular diseases, including hypertension and heart failure. Ingestion ...

Introduction Hand osteoarthritis (OA) is a prevalent joint disorder with limited treatment options. Accumulating evidence suggests that the antidiabetic drug metformin has beneficial effects on knee ...

The research on metformin and human longevity is scant, but that hasn’t stopped some people from experimenting with it. By Mohana Ravindranath A few years ago, Marc Provissiero, a movie producer ...

A comprehensive study presented at the Endocrine Society’s ENDO 24 annual meeting has revolutionized understanding of diabetes management during pregnancy. Following 10,117 mother-child pairs for up ...

ABSTRACT: Background: This study aimed to evaluate the bioequivalence of the two formulations of metformin 1000 mg XR tablets in healthy male volunteers under fasting conditions. Methods: This was a ...