June 19 is Juneteenth and Sickle Cell awareness day. Experts say the disease impacts 100,000 people in the U.S., and 90% of those cases are in the African American community. That’s why a blood drive ...

Although sickle cell disease (SCD) is not as widespread in the Philippines compared to other populations, it is still worth knowing what this disease is all about, especially as we observe World ...

Myocardial ischemia is often manifested by nonclassic symptoms in women. She had a history of non–transfusion-dependent α-thalassemia (hemoglobin H disease) complicated by acquired hemochromatosis.

Hemoglobin H disease (three gene defects): This form presents with moderate to severe anemia. “Symptoms often include chronic tiredness or fatigue, weakness, pale or yellowish skin due to jaundice, ...

The following is a summary of “Evaluated NSUN3 in reticulocytes from HbH-CS disease that reflects cellular stress in erythroblasts,” published in the April 2025 issue of Annals of Hematology by Liu et ...

Hemoglobin H disease. This type causes moderate to severe symptoms. These include fatigue and exercise intolerance. You may also have an enlarged liver or spleen, yellowish skin, and leg ulcers. You ...

Sickle cell disease stems from a mutation in the gene that makes hemoglobin, the protein in red blood cells that carries oxygen throughout the body. Orkin’s team and others revealed that hemoglobin ...

Spotlight On > ASH: Thalassemia Managing Non-Transfusion-Dependent Thalassemia Presents Challenges — Despite its name, non-transfusion-dependent thalassemia is not a mild form of the disease by ...

You might have mild symptoms or none at all. Hemoglobin H disease, when you have three missing or mutated genes. This causes symptoms that are moderate to severe.

Exosomal mRNA transfer from non-neuronal cells to neurons under hypoxia drives hemoglobin expression and preserves mitochondrial homeostasis as an intercellular protective mechanism.

Changes in levels of hemoglobin would result in alterations of cerebral blood flow (CBF). However, the impact of hemoglobin on CBF in moyamoya disease (MMD) remains largely unknown. This study sought ...