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Study reveals ATM kinase as the key driver of replicative senescence

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the protective ...

Pasithea Therapeutics Announces $1 Million Award by ALS Association to Study the Efficacy, Safety, and Tolerability of PAS-004 for Treatment of ALS

The ALS Association is the world's leading funder of amyotrophic lateral sclerosis (ALS) research ---- The Hoffman ALS Clinical Trial Awards ...

Pasithea Therapeutics Announces Completion of Cohort 7 in Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients, with Positive Safety, Pharmacokinetic (PK), an…

Zero Treatment Related Adverse Events observed during Cohort 7 (37mg capsules) DLT period – --Cohort 7 Pharmacokinetic (PK) ...
Frontiers

Mechanism and research progress of MAPK signaling pathway in myocardial fibrosis

1 First Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China 2 Department of Cardiovascular Diseases 1, The First Affiliated Hospital of Heilongjiang ...
Frontiers

Vitamin K protects against lipopolysaccharide-induced intestinal inflammation in piglets by inhibiting the MAPK and PI3K-AKT pathways

Background: The benefits of Vitamin K (VK) in mitigating inflammation have been well-established, while the underlying mechanisms remain not yet fully elucidated. This study aimed to investigate its ...