Myc is one of the most frequently mutated, widely studied, and overexpressed genes implicated in cancer. Most mutations in the myc gene lead to its constitutive expression. The myc gene codes for the ...

Novel Treatment Targets in Sarcoma: More Than Just the GIST MYC has proven to be a highly potent oncoprotein when it is overexpressed, but is also a pleiotropic transcription factor essential for ...

Scientists have learned that prostate cancers can vary significantly among patients and that there are often differences within each patient's tumor. However, the study published Aug. 28 in Nature ...

This is a preview. Log in through your library . Abstract The opposing transcriptional activities of the basic-helix-loop-helix-leucine zipper proteins Myc and Mad, taken together with information ...

Breast cancer is the most frequent malignancy among women worldwide, and all subtypes of breast cancer involve upregulation of the c-Myc gene, making it a compelling therapeutic target. G-rich regions ...

The MYC oncogene family plays an important role in neoplastic disease, and has been extensively studied over decades. Evidence showing the N-terminal and C-terminal regions of MYC can function as a ...

Androgen-regulated metabolome in prostate cancer. Background: Studies have shown a link between HMG-CoA reductase inhibitors (statins) and decreased cancer risk in various cancers including prostate ...

Sperm – in theory, you only need one good one to get the job done. Nevertheless, the average pair of human testicles is estimated to crank out about a trillion of these little cells over a lifetime, ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, No. 15 (April 9, 2013), pp. 6103-6108 (6 pages) The protooncogenes Akt and c-myc each positively regulate ...

Dublin, Dec. 23, 2021 (GLOBE NEWSWIRE) -- The "Proto Oncogene Protein C-MYC Inhibitors - Pipeline Insight, 2021" drug pipelines has been added to ResearchAndMarkets.com's offering. This report ...