If lifestyle, metformin, and a second medication do not result in goal glycemia, the next step should be to start, or intensify, insulin therapy (Fig. 1).

The UKPDS compared three classes of glucose-lowering medications (sulfonylurea, metformin, or insulin) but was unable to demonstrate clear superiority of any one drug over the others with regard ...

Top Alternatives to Ozempic That Are EffectiveReviewed by Dr. Craig Primack, MD, FACP, FAAP, FOMAOzempic is a medication approved by the FDA for individuals ...

Ozempic is an FDA-approved medication for people with type 2 diabetes. It’s often prescribed off-label for weight loss — that’s when a drug is prescribed for something it’s not FDA-approved for.

Most people start on a 2.5-milligram dose of tirzepatide and gradually increase up to a maximum dose of 15 milligrams. We’ve compared Mounjaro versus Ozempic if you want to learn more.

INDIANAPOLIS, June 16, 2025 /PRNewswire/ — Eli Lilly and Company (NYSE: LLY) today announced that the highest approved doses of Zepbound (tirzepatide)—12.5 mg and 15 mg—will soon be available in ...

The selected metformin doses were based on a review of the available literature, which indicates that metformin plasma concentrations in patients receiving therapeutic doses (1,500 mg/day) do not ...