The authors describe an interesting approach to studying the dynamics and function of membrane proteins in different lipid environments. The important findings have theoretical and practical ...

Inside nearly every cell of your body, the tiny F1 motor works non-stop to create adenosine triphosphate (ATP), the universal ...

VANCOUVER, British Columbia--(BUSINESS WIRE)--Variational AI, the company behind Enki™, an advanced foundation model for small molecule drug discovery, today ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

This process is costly, time-consuming, and has a low success rate. KAIST researchers have developed an AI model that, using only information about the target protein, can design optimal drug ...

First came AlphaFold. Now comes AlphaGenome for DNA. When scientists first sequenced the human genome in 2003, they revealed the full set of DNA instructions that make a person. But we still didn’t ...

In April, Northwestern University cardiologist Dr. Rod Passman learned the National Institutes of Health had abruptly halted funding for a $37 million trial testing a new way to treat dangerous heart ...

The new model addresses the challenge of identifying novel small molecules that meet multiple product criteria, an essential requirement for pharma and agriculture applications REHOVOT, Israel, June ...

Researchers at the Massachusetts Institute of Technology and Recursion Pharmaceuticals Inc. have released an open-source AI model that can predict the binding strength of small molecules as well as ...

In traditional drug and agriculture chemical research, scientists usually test one factor at a time—first checking if a compound works, then later testing for safety and stability. This step-by-step ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Molecular glues hold immense therapeutic promise by stabilizing ...

Boltz-2 is an open-source biomolecular model achieving near-FEP accuracy with 1000x faster predictions for structure and binding affinity. MIT and Recursion have released Boltz-2, the first ...