Mechanism of action of p28, a first-in-class, non-HDM2 mediated peptide inhibitor of p53 ubiquitination. This is an ASCO Meeting Abstract from the 2011 ASCO Annual Meeting I. This abstract does not ...

These include ACLY, ACC, and FASN, regulated by transcription factor SREBP1c. In HCC, SREBP1c can be overexpressed by P13K/Akt/mTOR pathway activated by CD147 and its downstream molecules, such as ...

Figure 1: Key signaling pathways and targeted factors in dysregulated BC. This figure illustrates the major signaling pathways and their intricate crosstalk in BC, focusing on the GPCR, RTKs, ...

Circadian rhythms are endogenous oscillations widely present in living organisms, typically following approximately 24-hour ...