LRK-4189, which targets PIP4K2C, a key cancer cell fitness target, is being developed for microsatellite stable (MSS) ...

Lin Hongxuan, the team's lead scientist, explained the mechanism through which rice senses and adapts to high temperatures. When exposed to heat, a key enzyme, diacylglycerol kinase 7 (DGK7), on the ...

Research confirms creatine's safety, highlighting misinformation and low-quality supplements as primary concerns over cancer ...

Molecular glues are revolutionizing cancer therapy by targeting undruggable proteins for degradation, enhancing precision ...

Breast cancer remains a predominant global health challenge for women, with late-stage diagnosis being a key contributor to its high mortality. This ...

The authors identify the Bearded-type small protein E(spl)m4 as a physical and genetic interactor of TRAF4 in the Drosophila wing disc. These valuable findings with potential biomedical relevance are, ...

Hepatocellular carcinoma (HCC) is the sixth leading cause of cancer-related mortality worldwide.1 Despite therapeutic ...

Over the past two decades, thoracic oncology has undergone a profound transformation, moving from limited chemotherapy ...

Globally, metabolic dysfunction-associated steatotic liver disease (MASLD) is now the most common chronic liver disease, affecting up to one in three people in the general population, with an ...

Chronic conditions and rare diseases in the aging population present an urgent and expanding challenge within the U.S. healthcare system, especially ...