RB Isaac Guerendo was dealing with a hamstring injury. Here are the latest updates leading up to Week 17’s game vs. the Lions ...

Way back in Week 4, 49ers rookie guard Dominick Puni had the wind knocked out of him and had to miss a snap. He hasn’t been ...

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With nothing left to play for this season, the 49ers will have to hope that Brock Purdy grows from a challenging 2024 ...

Nolan Bianchi, John Niyo, Richard Silva and Bob Wojnowski of The Detroit News offer predictions for Monday's Lions-49ers game ...

Coach Dan Campbell stood at the podium after Detroit blew a 17-point lead to San Francisco in last season's NFC title game ...

San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN ...

Who are the 10 greatest San Francisco 49ers of all time? FOX Sports Research compiled the list of Niner greats.

Detroit Lions coach Dan Campbell remains haunted by January's NFC Championship Game in San Francisco. For Campbell, it still ...

Week 17 of "Monday Night Football" features the Detroit Lions and the San Francisco 49ers. Check out how to watch on ESPN.

NFL Week 17 odds, picks, predictions, TV channel, streaming information for Monday Night Football game between Detroit Lions ...

Tua Tagovailoa threw for 215 yards and a touchdown, Jason Sanders nailed five field goals, and the Miami Dolphins kept their ...