The human P2X4 receptor plays an important role in chronic pain, inflammation and some types of cancer. Researchers at the ...
An ongoing outbreak of highly pathogenic avian influenza has affected more than 184 million domestic poultry since 2022 and, ...
The approval of the GLP-1 receptor agonist semaglutide for weight regulation in January 2023 ushered in a new era of obesity therapy. In recent months, however, drug regulatory authorities have also ...
Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...
For patients with type 2 diabetes, there is an association between glucagon-like peptide-1 receptor agonist (GLP-1 RA) use ...
The sweet-taste receptor might be the first stop in a metabolic surveillance system for sugar. The receptor is also expressed in certain intestinal cells, where it may facilitate glucose absorption ...
Study: ‘Suicidal’ mechanism discovered in ion channel receptors enables the sensing of heat and pain
BUFFALO, N.Y. – The ability to accurately detect heat and pain is critical to human survival, but scientists have struggled to understand on a molecular level exactly how our bodies sense these ...
When Christopher Klebanoff, MD, came to Memorial Sloan Kettering Cancer Center (MSK) from the National Cancer Institute in 2016, he was focused on a singular goal: bringing the promise of cellular ...
The researchers captured eight unique structural models and 16 cryogenic electron microscopy maps of the receptor with both naloxone – which reverses the effects of an opioid overdose – and loperamide ...
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