Iran and Israel exchanged more deadly missile strikes overnight Friday after Israel mainly attacked Iranian nuclear and military targets one day earlier.

The Iron Dome is designed to protect Israeli citizens by launching guided missiles to intercept incoming rockets and other short-range threats in mid-air.

DUBAI, United Arab Emirates (AP) — Israel’s defense minister warned Saturday that “Tehran will burn” if Iran continues firing missiles, as the two countries traded blows a day after Israel launched a blistering surprise attack on Iranian nuclear and military sites, killing several top generals.

Iranian officials on Saturday signaled they could walk back their decision to not attend upcoming nuclear talks with the U.S., but said further negotiations were likely “meaningless” as the nation exchanges fire with Israel.

DUBAI, United Arab Emirates — Israel’s defense minister warned Saturday that “Tehran will burn” if Iran continues firing missiles on Israel after at least three people died and dozens were wounded Saturday morning, following a series of blistering Israeli attacks on the heart of Iran’s nuclear program and its armed forces.

Iranian state media report more explosions, with blasts heard in Tehran, as Israel says its air force is hitting military targets.

The first wave of Israeli strikes killed 78 people and wounded 320, according to Iran's ambassador to the United Nations. The Israeli military said three people were killed and 76 wounded since Iran began its retaliatory attacks.

Israel's initial assault used warplanes and drones to hit key facilities and kill top generals and scientists.

Defense Sec. Hegseth confirmed that President Trump is "dialed in" to the Israel-Iran conflict on "Fox & Friends" Friday and assured that this is not an "autopen moment" for the president.