Experts suggest the U.S. has a strategic opportunity to leverage Iran's weakened position for a nuclear deal after Israel's targeted strikes on Iranian nuclear and military sites.

"The full strength and might of the U.S. Armed Forces will come down on you at levels never seen before," Trump warned.

Israel has launched hundreds of air strikes since the early hours of June 13th. Iran has responded with salvoes of ballistic missiles and drones, although only a handful have penetrated Israel’s defence systems.

A series of loud explosions are heard in central Israel as the military says it carried out intelligence-based strikes in Tehran.

The U.N. atomic energy agency has given several updates on Iran's nuclear facilities on Saturday. It is reporting that the Isfahan nuclear complex was hit several times on June 13 and that four critical buildings were damaged there.

Amid escalating tensions and reports of an impending Israeli strike, US President Trump reaffirms commitment to a diplomatic resolution for the Iran nuclear issue.

Israel pinpointed Iranian commanders in their homes and killed them, some with drone strikes launched from inside Iran — an echo of what Ukraine recently achieved inside Russia. How far the nuclear programme has been set back won’t be clear for a while.

Israel signaled no letup in its campaign to destroy Iran’s nuclear capabilities, with risks in the oil-rich region rising as the nations bombarded military and civilian targets alike.