A single treatment of viral vector-delivered CAR-A construct in mice with existing plaque saturation cut the amount of amyloid plaques in half.
Using rodent and cellular models, the researchers showed that tanycytes take up tau from the CSF and release it into pituitary portal capillaries.
Ongoing research aims to confirm the mechanism by which ICP4 fluidizes the nucleus, which could indicate specific targets to counter viral replication.
From analytical control through downstream processes to manufacturing, BsAbs present challenges in protein expression, purity, and stability.
The new center offers immersive, hands-on access to advanced cryo-EM technologies designed to accelerate structural insights.
The CNBC Cures Summit, held in New York earlier this week, opened with a simple but urgent premise: every step forward changes someone’s life.
Researchers say study findings have highlighted biomarkers that could help improve early diagnosis of esophageal cancer, when it is easier to treat.
HIV-seq identifies key differences in HIV-infected cells before and after starting antiretroviral therapy to support treatment research.
Researchers at Sanofi report that cas-CLOVER (deactivated Cas9 fused to the C-terminus of Clostridium Clo051) gene editing has the potential to notably enhance recombinant protein production in ...
Researchers based in Germany have developed a perfusion process for the manufacture of oncolytic viruses. The team from the Max Planck Institute says that the new approach aims to improve virus titers ...
Fully automated “self-driving” process development labs are an attractive idea, but human expertise and oversight will always be needed.
Seal’s Will Moss explains why chain-of-identity failures threaten patient safety and cell and gene therapy scale-up.