Substance use and substance use disorder (formerly substance abuse) differ by the frequency of use and the effect on a person ...

In The Substance, Demi Moore plays an aerobics TV star who turns 50 and is promptly ousted from her gig in Hollywood. She and Margaret Qualley duke it out in this excruciating body horror tale.

Two new films seem to be in dialogue: In The Substance, Demi Moore is a Hollywood star chasing eternal youth. The dark comedy A Different Man centers on a New Yorker with a rare genetic condition.

The Substance (Courtesy of MUBI)The actor also told The Times that it wasn’t until after shooting for G.I. Jane wrapped that she finally experienced a “huge shift” and came to terms with how ...

Substance use was implicated in more than half of all adult drownings in baths or hot tubs in the last 10 years, according to ...

The Substance Rated R for guts and gore and nudity galore. Running time: 2 hours 20 minutes. In theaters. The Substance. NYT Critic’s Pick. Find Tickets.

Elon Musk shared the results of a rapid drug test on Tuesday, June 17, which show he tested negative for ketamine, ecstasy, ...