The Detroit Lions and San Francisco 49ers play Monday, Dec. 30, at the 49ers' Levi's Stadium in a game on the NFL Week 17 schedule. Which team will win the Monday Night Football game? Check out ...

While the 49ers have been dealing with injuries all season, they added a key player to the list in last week's loss to the Lions, as quarterback Brock Purdy hurt his right elbow in the closing ...

George Kittle didn't have a catch. All three players, though, made big plays in the second half as the San Francisco 49ers rallied from 17 points down to beat the Detroit Lions and advance to the ...

And yet you guys managed to bring thoughtfulness — and even some mirth — to this week’s San Francisco 49ers holiday mailbag. Well done! I hope your stockings were full of frankincense and myrrh.

Bo Nix and the Denver Broncos are in the thick of the AFC wild-card race, and the first-round pick has done an admirable job operating Sean Payton's scheme as a rookie quarterback. But something's ...

A rematch of last year's NFC Championship Game, the Detroit Lions vs. San Francisco 49ers was expected to be one of the best games of the season when the schedule was released. Now though ...

The San Francisco 49ers, with a 6-9 record, have had a difficult season. They are out of any chance of making it to the playoffs after last week’s game. The victories by the Rams and the ...

Purdy had completed a 17-yard pass to Jauan Jennings to the 49ers’ 47-yard line just before the two-minute warning with the 49ers trailing 22-17. They had all their timeouts, George Kittle ...

It's not the showdown of NFC powers the schedule-makers hoped for back in May, but when the Detroit Lions visit the San Francisco 49ers next Monday night in a rematch of last year's NFC ...

The Detroit Lions visit the San Francisco 49ers on Monday at 8:15 p.m. ET, in a matchup featuring a pair of the top offensive performers in the NFL in Jahmyr Gibbs and George Kittle. The Lions ...