The 49ers likely have no intention of playing starter Christian McCaffrey in the preseason, backup Isaac Guerendo is out for ...

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

The 49ers may provide an indication of how they're feeling about their RB depth in the days ahead. If they sign another ...

San Francisco's Christian McCaffrey revealed the unteachable traits that make 49ers QB Brock Purdy "so special." ...

The 49ers are limiting Christian McCaffrey's training camp reps to keep the running back healthy for the season opener and ...

Mackenzie Brooks and the Inside the Lines Team break down where every NFC West team's season is most likely to end and how to ...

Two top contenders this year face off in the preseason opener, with the San Francisco 49ers hosting the Denver Broncos. However, many fans are wondering whether stars Christian McCaffrey and Bo Nix ...

Since quarterback Brock Purdy took over as the 49ers' starting quarterback midway through the 2022 season, the team's offense has not only consistently been among the league's best--especially during ...

The San Francisco 49ers cannot last more than a few months without losing their entire running back room to injury, even in ...

According to Pro Football Reference, Purdy ended the 2024 regular season ranked seventh in the NFL among qualified players ...

This is the second installment on fantasy drafting. Today it's running backs. (Find my article on wide receivers here.) There are more good receivers than running backs—and/or there is an earlier and ...

San Francisco 49ers’ Christian McCaffrey (23) runs with the ball against Kansas City Chiefs’ Leo Chenal (54) in the first half at Levi’s Stadium in Santa Clara, Calif., on Sunday, Oct. 23, 2022.