Isomeranzin (ISM) binds to Gnas, activating adenylyl cyclase and elevating intracellular cAMP levels. This activation ...

I haven't taken a survey, but I feel pretty confident that nobody at PC Gamer is more afraid of spiders than I am. They petrify me—unless they manage to get on me, at which point I flail around like I ...

Purpose: Mitophagy is an important process in brain damage, and the precise impact on a traumatic brain injury (TBI) model remains unclear. AMP-activated protein kinase (AMPK) regulates mitochondrial ...

Department of Biomedical Sciences, New York Institute of Technology, College of Osteopathic Medicine, Old Westbury, NY, United States AMP-activated protein kinase (AMPK) is a central regulator of ...

In preclinical studies, Biolexis' oral GLP-1 receptor agonist, BLX-7006, resulted in a 29% reduction in weight in diet induced obesity mice. In GLP toxicology studies, BLX-7006 demonstrated no ...

Our findings demonstrate that SOX9 overexpression alleviates hepatic lipid accumulation in MASH by activating the AMPK pathway. These results highlight SOX9 as a promising therapeutic target for ...

Few ’90s tech sites other than Ars Technica are still operating here in 2024, and today, there’s one fewer. AnandTech, a staple of CPU and GPU news and reviews since 1997, will stop publishing today, ...

The film, directed by Justin Baldoni, who also stars opposite Blake Lively, hits theaters Friday. By Carly Thomas Associate Editor Following the New York premiere of It Ends With Us on Tuesday evening ...

Posts from this topic will be added to your daily email digest and your homepage feed. Microsoft’s latest 2-in-1 is all in on Arm, and it’s the closest the company’s come to merging the power of a ...

ABSTRACT: Epidemiological studies indicate that treatment with metformin, an AMP-activated protein kinase (AMPK) activator, reduces the incidence of cancers. Activation of AMPK has also been reported ...