Patients with antiphospholipid antibodies (aPL) are at increased risk for arterial or venous thrombosis. There is, however, significant heterogeneity among patients according to clinical and ...

There is controversy regarding the appropriate strategy (anticoagulation vs aspirin) for stroke prevention in low-risk patients (CHA2DS2-VASc score of 0–1). Novel anticoagulants include ...

1 Department of Medicine, University of Wisconsin School of Medicine and Public Health, 3116 MFCB, 1685 Highland Avenue, Madison, WI 53705, USA. 2 Division of Electrophysiology and Cardiovascular ...

Inclusion criteria: Adults (18 years old or older) taking antiplatelet drugs for at least 2 weeks; scheduled for elective or emergency neurosurgery under general anaesthesia (craniotomy, spinal cord ...

Overuse of non-aspirin NSAIDs and acetaminophen increases kidney cancer risk by 25-66%, with long-term use damaging kidneys, ...

In an article for The Times, Dr Porter notes: "Nice estimates that 1-2 per cent of the population have medication-overuse headache (MOH) - frequent headaches caused by painkillers and migraine ...

Resistance and nonresponse to aspirin dramatically decreases its therapeutic efficacy. To overcome this issue, a small-molecule thrombus-targeting drug delivery system, aspirin-Arg-Gly-Asp-Val (A-RGDV ...

High-dose aspirin (HDA) is used with intravenous immunoglobulin (IVIg) in Kawasaki disease (KD). Practice regarding HDA varies, and it is unclear whether HDA duration affects the long-term course.

Additionally, older adults receiving IV ibuprofen were administered on average 33.30mg of morphine vs 43.38mg for those receiving placebo, resulting in a 23.2% reduction in total postoperative ...

Methods Patients were randomised (2 : 1 ratio) to receive naproxen (NPX) 1000 mg daily plus either IFX 5 mg/kg or placebo (PBO) at weeks 0, 2, 6, 12, 18 and 24. The primary efficacy measure was the ...

A major international study has found that heart patients, particularly seniors, may benefit more from newer blood-thinning medications called P2Y12 inhibitors than traditional aspirin therapy ...

P2Y12 inhibitors, such as clopidogrel and ticagrelor, are typically prescribed alongside aspirin in a dual therapy approach following percutaneous coronary interventions (PCI), a common procedure to ...