Researchers at UT San Antonio have uncovered new details about electrical signals happening within nerve cells, deepening scientists' understanding of the brain.
Researchers at National Taiwan University have uncovered, for the first time at atomic resolution, how the human proteasome ...
Background Hereditary haemorrhagic telangiectasia (HHT) and juvenile polyposis syndrome (JPS) can be caused by SMAD4 pathogenic variants. SMAD4 is a common transcription factor of the BMP/TGFβ ...
Researchers from the German Cancer Research Center and the University of Freiburg show how certain painkillers influence the iron metabolism of liver cancer cells and can thus contribute to iron ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. FAM134/RETREG family members are ER-phagy ...
1 School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China 2 Queen Mary School, Nanchang University, Nanchang, China Fibroblasts are integral to the pathological ...
The transforming growth factor-β (TGF-β) superfamily (TGF-β-SF) comprises over 30 cytokines, including TGF-β, activins/inhibins, bone morphogenetic proteins (BMPs), and growth differentiation factors ...
Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a normal ...
Neuroblastoma is a solid tumor that occurs in children. When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment increased survival by 10 ...
(L to R) Co-first and co-corresponding author Min Pan, PhD, co-first author Yinwen Zhang, PhD, St. Jude Department of Computational Biology, co-corresponding author John Easton, PhD, St. Jude ...
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