Five million children are impacted by a parent's cancer diagnosis, according to the CDC, and two Bay Area leaders are ...
Researchers at UT San Antonio have uncovered new details about electrical signals happening within nerve cells, deepening scientists' understanding of the brain.
Lin Hongxuan, the team's lead scientist, explained the mechanism through which rice senses and adapts to high temperatures. When exposed to heat, a key enzyme, diacylglycerol kinase 7 (DGK7), on the ...
Isomeranzin (ISM) binds to Gnas, activating adenylyl cyclase and elevating intracellular cAMP levels. This activation ...
This important work substantially advances our understanding of the molecular mechanisms underlying the timing of the initiation of metamorphosis of the Ciona ascidian tadpole larva. Through the ...
Department of Pharmacology, Qingdao University School of Pharmacy, Qingdao, China Background: Alcohol use disorder (AUD) and post-traumatic stress disorder (PTSD) exhibit a significant degree of ...
The storage and retrieval of information encoded in the nervous system are often accompanied by morphological changes in the participating neurons. During brain development, neurite elongation and ...
Cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) are critical second messengers involved in numerous cellular functions, including metabolism, the endocrine system, and ...
E3 ubiquitin ligase CHIP facilitates cAMP and cGMP signalling cross-talk by polyubiquitinating PDE9A
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The carboxyl terminus of Hsc70-interacting ...
BBPH, bear bile powder high dose; BBPL, bear bile powder low dose; DSS, dextran sulfate sodium; NC, normal control; 5-ASA, 5-Amino salicylic acid. Ulcerative colitis (UC) is a chronic autoimmune ...
This landmark study sheds light on a long-standing puzzle in Protein kinase A activation in Trypanosoma. Extensive experimental work provides exceptional evidence for the conclusions of the work, ...
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