Disruption of motile cilia-driven extracellular fluid flow can result in devastating disorders like hydrocephaly, child-onset epilepsy, respiratory distress, and female infertility. Yet, despite the ...

Cilia — tiny hair-like organelles attached to the cell surface — are located on most polarized cells and have been adapted as versatile tools for various cellular functions. Several molecular ...

Cilia movement is driven by an array of longitudinal microtubules arranged in 9 doublets around a central pair. A basal body anchors these microtubules inside the cell.

One essential component of each eukaryotic cell is the cytoskeleton. Microtubules, tiny tubes consisting of a protein called tubulin, are part of this skeleton of cells. Cilia and flagella, which ...

The primary cilia observed in this study originated from both animal and human beta cells. The researchers investigated how the skeletal structure (axoneme) formed from microtubules is organized.

After her late-night observation, Hughes and colleagues began their investigation by imaging primary cilia in human and mouse pancreatic islets. Each cilium is typically organized in a specific ...

Cilia consist of an outer structure of nine pairs of microtubules, long tube like molecules that are part of the cell cytoskeleton, arranged into a circle.

The primary cilia observed in this study came from both animal and human beta cells. The researchers examined how the skeletal structure (axoneme) formed by microtubules is organized. They discovered ...

Circular rings around its base form the transition zone of the cilium, from which nine parallel microtubules project into the extracellular space. About halfway through, the microtubules wind around ...

Some cilia that had their membranes removed were subsequently examined to define the number and size of microtubules, other structural components repeating in such cilia, and chirality.