It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells. Researchers at RPTU have now investigated the detailed effects of such imbalances ...

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic ...

President Trump signs an executive order Monday banning all federal funding towards “dangerous" gain-of-function research in China, Iran and other countries, and blocking all federal funding for ...

Objectives: We undertook a systematic literature review as a background to the European League Against Rheumatism (EULAR) recommendations for conducting clinical trials in anti-neutrophil cytoplasm ...

It also includes cytosol, which is the fluid part of cytoplasm. Since prokaryotes lack membrane-bound organelles, all biochemical reactions, such as energy production and metabolism, occur within the ...

Asthenozoospermia, characterized by reduced sperm motility, is a common cause of male infertility. Multiple morphological abnormalities of the sperm flagella (MMAF) represent a severe and genetically ...

In this article, we focus on two related types of immune cell – the monocyte and the macrophage. We discuss what monocytes and macrophages are, how they are generated, their functions in the body and ...

Many enzymes undergo major conformational changes to function in cells, particularly when they bind to more than one substrate. We quantify the large-amplitude hinge-bending landscape of human ...

New findings published in Molecular Cell provide details about the hidden organization of the cytoplasm - the soup of liquid, organelles, proteins, and other molecules inside a cell.