Pharmaceutical Technology on MSN
RNA-targeting small molecules: A new frontier of drug discovery
With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology ...
G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs. These receptors regulate a wide ...
A recent study shows that computer algorithms can be used to find molecules that can be developed into anti-inflammatory drugs. In the article, the researchers also describe how the same strategy can ...
Photosensitive drug molecules that can be activated by visible green light could lead to novel precision therapeutics to treat cancer and other diseases. Researchers at the Institute for Advanced ...
ADCs combine antibodies with drug payloads for targeted therapy, but complex manufacturing requires monitoring CQAs across multiple entities.
A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl ...
As the science of drug discovery has grown in scale and gotten more complicated, so have the drug molecules themselves. But there’s a promising class of drugs made of just a handful of atoms that ...
Amide bonds are common in drugs because they are chemically stable, form readily and are biocompatible. They also help ...
AI automation throughout the drug development pipeline is opening up the possibility of faster, cheaper pharmaceuticals. At 82 years old, with an aggressive form of blood cancer that six courses of ...
New approaches to obesity treatment are emerging as scientists target underexplored metabolic pathways with the help of artificial intelligence. Demand for better obesity medicines is rising quickly, ...
How can we improve drug specificity? Larger, more complex drugs may be the way to target ‘undruggable’ cell targets, but how are these drugs taken up by cells? Researchers at the University of ...
Understanding the thermodynamic basis of ligand recognition by G-protein-coupled receptors (GPCRs), especially in terms of ...
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