One of the greatest revolutions in the field of pain medication was the isolation of morphine from the opium poppy in the ...

Chirality: like a right hand and a left hand, two molecules can have the same composition, but a different shape and ...

A recent study led by Paul DeCaen, Ph.D., associate professor of Pharmacology, has identified novel molecular mechanisms by ...

Scientists at The Wistar Institute have discovered how a key protein from the Epstein-Barr virus (EBV), EBNA-LP, ...

The SAIR database is designed to help scientists train AI models to better predict protein-ligand binding affinities for drug discovery.

The structure showed 12 transmembrane helices in two pseudo-symmetric bundles and two periplasmic subdomains. Experiments showed that the coiled-coil domain, whose predicted model extends from one of ...

MIT and Recursion have released Boltz-2, the first biomolecular co-folding model that simultaneously predicts molecular structure and binding affinity with remarkable accuracy, approaching that of ...

Discover the science behind runner’s high, why it feels euphoric, and how to achieve it—plus, why humans adapted to have this evolutionary advantage.

Researchers made small tweaks to the molecular structure of LSD to see if it could be turned into an effective brain-healing treatment.

The endocannabinoid is a complex system that still isn't fully understood. We'll go over what experts do know about it, including how it works, the ways it interacts with cannabis, and theories ...

BRINP2-related peptide, or BRP, is a naturally occurring molecule that can suppress appetite and promote weight loss in mice and pigs.

But this year, scientists managed to wrangle it into a water-soluble organometallic complex for the first time, making chemical analysis more manageable (Nature 2024, DOI: 10.1038/s41586-024-07267-6).